Familial SCAD risk factors highlight the necessity for cardiologists to evaluate family histories during patient assessments. Familial clustering in SCAD cases suggests a genetic component that can be critical to understanding potential risks for other family members. Research provides evidence for genetic susceptibility, highlighting the importance of comprehensive pedigrees to guide proactive surveillance of at-risk relatives.
Coronary angiography remains the gold standard for confirming SCAD, facilitating visualization of dissection flaps or intramural hematomas and distinguishing these from atherosclerotic narrowing. As noted in the earlier report, adjunctive imaging modalities such as intravascular ultrasound and optical coherence tomography can clarify equivocal angiographic findings, especially when separating SCAD from other acute coronary syndrome presentations with or without ST-segment elevation.New Genetic Insights in SCAD: Implications for Cardiology Practice
07/21/2025
Key Takeaways:
- Familial predisposition plays a critical role in SCAD, necessitating thorough family history evaluations.
- Coronary angiography remains the gold standard for SCAD diagnosis, supported by advanced imaging techniques.
- Endurance athletes with myocardial fibrosis face increased SCAD risk; regular cardiac evaluations are essential.
- Genetic insights are paving the way for more personalized SCAD prevention and management strategies.